Autoantibodies and Autoimmunity : Molecular Mechanisms in Health and Disease

No. Klas	:	571.96/Pol/A
Pengarang	:	K. Michael Pollard
Penerbit	:	WILEY-VCH Verlag GmbH & Co., Germany, 2006
Kolasi	:	635 p. : tab. ; fig. ; bibl. ; ind.
Digital Copy	:	5
Pinjaman Aktif	:	0
Synopsis	:	The basis for this book was a chapter written for the 2nd edition of R.A. Meyers’ Encyclopedia of Molecular Cell Biology and Molecular Medicine. Entitled Autoanti- bodies and Autoimmunity, that chapter sought to take a different approach in re- viewing the broad field that encompasses autoimmunity. This was in part due to my own research experiences, but also due to the realization that autoimmunity, and autoantibodies in particular, have contributed to more than just the medical sciences. Historically autoantibodies have served as indicators of an autoimmune re- sponse and early studies focused on their clinical and diagnostic significance. Today many autoantibody specificities contribute as diagnostic and prognostic indicators in clinical medicine. The burgeoning numbers of known autoantibod- ies has revolutionized methods of detection leading to development of multiplex assays capable of identifying numerous diagnostically important autoantibodies in a single assay.