Cambridge University Press, United of Kingdom, 2006
Kolasi
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294 p.: tab. ; fig. ; bibl. ; ind.
Digital Copy
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5
Pinjaman Aktif
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0
Synopsis
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This is the first dedicated, in-depth account of trophoblast: the tissue derived from the fertilised
egg that nourishes and protects the developing fetus. The cells of the trophoblast have many
unique qualities, and exhibit great variability across different species. It has a fascinating role in
the development of the placenta and as a regulator during early growth of the embryo. These
aspects are all fully covered as well as studies on why it is not rejected by the mother as ‘foreign’
tissue. Disorders of trophoblast during development also manifest themselves in several clinical
conditions during pregnancy, including gestational trophoblastic disease and pre-eclampsia.
From stem cells through to epigenetics, implantation and X-chromosome inactivation, there is
still a lot to be learned about trophoblast: this volume provides an up-to-date summary of the
state of current knowledge and offers some glimpses as to future development on the scientific
and clinical front.